I just installed Vanguard again. I am on x32 and played about 40mins with no issues. IQ is the same, FPS is the same. It's more choppy on occasion and there are a lot more people about on the servers now. I'll stress test it more when I have time.
I am going to try EQ 2 tomorrow. I have to install and patch it again. I avoided that with VG by sticking it on my D drive then returning it to C and using the install disk to update my registry. I forgot to do that with EQ 2.
I will probably install Doom III again to test OGL.
BTW if it hasn't been said Firefox functions perfectly fine under Vista x32. As do spywareblaster and ad-aware SE.
EDIT: Tried Dusk @ 1680x and got 16FPS
Something is up.