The below were pulled off this website's review-
Min frame examples-
Besides much better min frame rates you can also run 16xQ AA much easier at lower resolutions-
So the card's usefulness is not only restricted to very high res.
The card also does much better with Transparency AA-
I've tried both SLi and Crossfire. I've always vastly preferred the feel of a single strong GPU. No profiles, no glitches, not microstutter, and beastly AA capability.
In closing, there really isn't a right or wrong as far as the GTX 280 goes, there is only a right or wrong for you.