Why are people so worried about the 4 cities right now? Now correct me if I'm wrong but aren't they used for endgame content really? Why are we worrying about endgame content for a game that wont be out for months? Mythic will have time to add them in.
As for the careers that will be delayed...I played a broken ass paladin in WoW since nearly release so here is my take on it...If the class don't work then take it out, make it work and add it later. I would rather have 20 good classes over 20 good classes and 4 broken ones.
Mythic has already stated the cities will be patched in. They aren't so sure about the classes, but I'm sure they will come up with something.
On a side note, woot got in closed beta today!