On my machine neither 180.* is ok nor is any of the beta releases.
Can you tell me, which dirver version of 180.* you used to start a wine game a second time with xinerama enabled?
Disabling Xinerama is no solution IMHO, because the TwinView mode is extremously buggy and I can't really play without having effects like:
- The game is centered across both screens (one half on each screen)
- The game completely takes other both screens
- The second screen is blanked and therefore unusuable
And only using one screen is no solution, too.