This game looks pretty cool:
They're calling it an Action RPG. Its made by Obsidian, who made Knights of the Old Republic 2, Neverwinter Nights 2 and were once Black Isle, who made Fallout, Fallout 2, Planescape: Torment, and Icewind Dale.
Alpha Protocol doesn't look like any of those games but it looks interesting.
The gameplay video reminds me of a combination of Mass Effect and Splinter Cell.