It appears that a few people are running the patch successfully:
I think it's the right thing to do. It's a shame that the vga arbiter is opt-out in nature, since the overwhelming majority of video cards have their own relocatable address space to communicate with each card independently without toggling the enable bits for each card in a round-robin loop. It would have probably made more sense for drivers to declare that they need that facility, rather than declare that they don't.
I'm going to post this to the rpmfusion mailing list if no one has any objections.