First, clean up xorg.conf
Option "Coolbits" "1"
Then, create a script you can run on login with something like this.
nvidia-settings -a GlyphCache=1 -a PixmapCacheRoundSizeKB=4096
It's important to take note which options are default and which options are, well, optional, and use only those. If you don't do that, you won't know which options make a difference.
Also, try putting your xorg.conf file and other bits of code in the code tags, makes it 100x easier to read