Another distro release but this time it's Fedora. This is a user friendly distro that is FOSS and upstream based so you'll have to get your proprietary software from rpmfusion http://rpmfusion.org/
Fedora is more a cutting edge distro. You can enable the experimental Btrfs(an experimental new filesystem with backup snapshot support) from the DVD(not enabled by default). Fedora comes with experimental 3D support(not enabled by default) for various NVIDIA cards.
Fedora(Redhat) contribute a lot to upstream development.
Live CD's - http://fedoraproject.org/en/get-fedora-options#desktops
DVD - http://fedoraproject.org/en/get-fedora-options#formats
How to use Fedora on a USB stick - https://fedoraproject.org/wiki/How_t...d_use_Live_USB