Originally Posted by Slytat
I've had this happen before (not with the 480s but with 280s). Uninstalling PhysX and Nvidia's video drivers and then using driver sweeper and finally reinstalling everything fixed it for me (obviously with the requisite reboots in between).
And just to be clear, are you using 275.15? There were unofficial versions 257.07 and 257.76 but they were no good for gaming from what I've read.
Yes, 257.15 (edited version # typo). The reboots are a hassle, but so far it's worth it. Smooth game play, no crashes and great DX11 effects - it's all I ask for.