I'm using wine on FreeBSD amd64 with this method
. The x86 version of the driver is installed in the 32-bit jail. This setup works, but some times quitting a 3d game swaps the colours on my screen like this: http://www.youtube.com/watch?v=cU_BP-JgxDI
Logging out of GNOME and back in cures it. I'm currently running 256.44 with a GTS 250, but an 8600GT exhibited the same problem.