I use datalock, and have for years now.
I think the biggest difference between Datalock and any other encryption program is that it comes from a old and reputable company, Zonealarm whose free firewall I have been using for years.
The other big difference is the support. Got a problem or questions with Datalock, and just pick-up the phone. The problem with Truecrypt is no support.
Also, PC Mag did a great review of Datalock:
and I see on the Datalock page they have a 60 day free trial:
Although, I don’t know how anyone would test the trail…
Great software though.