I'm not familiar with Maya in WIndows, however I have used 4.5 in Linux and no special configuration was necessary for the application to utilize the nVidia GLX. You do need to install the nVidia driver for accelerated GLX, then just install Maya. If you can be more specific about what kind of settings you wish to change or the effect of doing so, I might have an idea what it is you're after.
"..the triumph of evil is for good men to do nothing."
VIDIA video driver RPMs for Fedora
:: see yum repo at livna.org