Please do not use 295.40 or the security patch with GeForce 6, 7 or 8800GTX/GTS cards
We have been made aware of an interaction problem between the fix contained in the newest release any any card with a chip older than G80, inclusive. This includes the full GeForce 6 and 7 series as well as GeForce 8800GTX and first-gen 8800GTS. We are actively working on resolving this issue and will provide an update as soon as possible.
The symptoms can include graphical corruption, performance issues, crashes and temporary hangs.
The release should be perfectly safe to use with more recent cards than that; I'll update this thread ASAP.