I usually use 1024x768 and 4xAA with max Aniso. Or if that runs badly I swap to either 1280x1024 or 1600x1200 and power down the AA.
Folding for Beyond3D
"A lie gets halfway around the world before the truth has a chance to get its pants on."
Sir Winston Churchill
"Halflife2 got halfway around the world before Gabe had a chance to get his pants on."