I can run at maximum settings with 2xAA at 1024 with decent frame rates. I have a 5900xt, 2600xp, and 512 ram, I was rather suprised that it ran so well. This game is gorgeous, in full motion it looks incredible. I really hate sams running animation, and his face model, it looks completely different from the one staring at you in the menu. Not quite sure why. Awesome gameplay as well, and the voice acting is sweet.